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SCR siRNA encapsulated microbubbles

Based on

1 Articles
2016 Most recent source

Composition

1

phosphate buffer solution

PBS
Type Complex Compound
Formula
Role core
2

octafluoropropane

perfluoropropane
Type Single Compound
Formula C3F8
Role loaded material
3

mixture of substance based on (1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine/1,2-dipalmitoyl-sn-glycero-3-phosphatidic acid/1,2-dipalmitoyl-sn-glycero-phosphatidylcholine)

Type Complex Compound
Formula
Role layer
4

poly(ethylene glycol)-b-poly(L-lysine)/siRNA cationic micelles

mPEG-b-PLLys/SCR siRNA cationic micelles
Type Nano Material
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
acoustic stability

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Applications

Area Application Nanomaterial Variant Source
diagnostics

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
BALB/c nude mouse bearing human cervical cancer HeLa cells xenograft

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine
  • 1,2-dipalmitoyl-sn-glycero-phosphatidylcholine
  • 1,2-dipalmitoyl-sn-glycero-3-phosphatidic acid
  1. MrQXWBPxoMWNnwzuX1h
Product

SCR siRNA encapsulated microbubbles

Diameter: ~ 1750 - 2030 nm

Medium/Support: none

References

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