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random aptamer-functionalized osteogenic pleckstrin homology domain-containing family O member 1 siRNA-encapsulating lipid nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

1

HEPES buffer

Type Complex Compound
Formula
Role core
2

osteogenic pleckstrin homology domain-containing family O member 1 siRNA

siPlekho1
Type Biomolecule
Formula
Role loaded material
3

mixture of substance based on (1,2-dipalmitoyl-sn-glycero-phosphatidylcholine/1,2-dipalmitoyl-sn-glycero-phosphatidylcholine/C16 Ceramide-PEG2000/C16 Ceramide-PEG2000/Dlin-KC2-DMA/Dlin-KC2-DMA)

Type Complex Compound
Formula
Role layer
4

cholesterol

Type Single Compound
Formula C27H46O
Role loaded material
5

random aptamer-PEG2000-DSPE

Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
encapsulation efficiency

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Applications

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
female Sprague-Dawley rat

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Preparation

Method 1

Type: Physical formation
Source:
Product

random aptamer-functionalized osteogenic pleckstrin homology domain-containing family O member 1 siRNA-encapsulating lipid nanoparticles

Hydrodynamic diameter: 78.1 - 95.9 nm

Medium: water

Support: none

References

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