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Ce6-loaded RGD and TAT peptides-modified mesoporous silica nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

1

mesoporous silica nanoparticles

amine-functionalized MSN NH2-functionalized MSN positively charged MSN MSN
Type Nano Material
Formula
Role core
2

fluorescein isothiocyanate-labeled TAT peptide

(FITC)-C6-TAT
Type Biomolecule
Formula
Role layer
3

polyoxyethylene-maleimide

PEG1500-MAL
Type Polymer
Formula
Role layer
4

cyclo-(Arg-Gly-Asp-D-Tyr-Cys)

cyclo(Arg-Gly-Asp-D-Tyr-Cys) c(RGDyC) peptide c(RGDyC)
Type Single Compound
Formula C24H34N8O8S
Role layer
5

(17S,18S)-18-(2-carboxyethyl)-20-(carboxymethyl)-12-ethenyl-7-ethyl-3,8,13,17-tetramethyl-17,18,22,23-tetrahydroporphyrin-2-carboxylic acid

13-carboxy-17-(2-carboxyethyl)-15-carboxymethyl-17,18-trans-dihydro-3-vinyl-8-ethyl-2,7,12,18-tetramethylporphyrin Chlorin e6 chlorin e6 Chlorin Ce6
Type Single Compound
Formula C34H36N4O6
Role loaded material

Properties

General physical and chemical properties

Property Value Source
Ce6 release dependent on pH

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Catalytic properties

Reaction Value Source
singlet oxygen generation under light irradiation

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Applications

Area Application Source
medicine/veterinary

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Characterization

Method Source
UV

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Biological effects

Biological system Test details Source
BALB/c nude mouse with HeLa cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
  1. eZcszqy2EVKNHQh8cpuS0p
  2. rIpq0b94qN
Product

Ce6-loaded RGD and TAT peptides-modified mesoporous silica nanoparticles

References

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