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siRNA-loaded polyethylenimine-based nanopreparations

Based on

2 Articles
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

poly(iminoethylene)

polyethyleneimine polyaziridine PEI
Type Polymer
Formula
Role raw materials
2

siRNA duplex targeting Green Fluorescent Protein

GFP-siRNA
Type Biomolecule
Formula
Role raw materials

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • poly(iminoethylene)
  • water
  • siRNA
Product

siRNA-loaded polyethylenimine-based nanopreparations

Hydrodynamic diameter: ~ 220 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • siRNA duplex targeting Green Fluorescent Protein
  • poly(iminoethylene)
  • buffered HEPES glucose
Product

siRNA-loaded polyethylenimine-based nanopreparations

Hydrodynamic diameter: 188 - 194 nm

Medium: buffered HEPES glucose

Support: none

References

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