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cabozantinib-loaded poly(lactic-co-glycolic acid)-poly(ethylene glycol) nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

poly(lactic-co-glycolic acid)-poly(ethylene glycol)

PLGA-PEG
Type Polymer
Formula
Role carriers
2

cabozantinib

XL184
Type Single Compound
Formula C28H24FN3O5
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
cryo-electron microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
AsPC1 human pancreas adenocarcinoma ascites metastasis cells

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Preparation

Method 1

Type: Physical formation
Source:
Product

cabozantinib-loaded poly(lactic-co-glycolic acid)-poly(ethylene glycol) nanoparticles

Hydrodynamic diameter: ~ 80 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • poly(lactic-co-glycolic acid)-poly(ethylene glycol)
  • cabozantinib
  1. ZehMTco
Product

cabozantinib-loaded poly(lactic-co-glycolic acid)-poly(ethylene glycol) nanoparticles

Size: not specified

Medium/Support: none

References

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