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Cy5.5/doxorubicin-loaded cis-aconityl-linked cystamine-grafted hyaluronic acid nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

HA

Type Biomolecule
Formula
Role raw materials
2

2-[(2-aminoethyl)disulfanyl]ethan-1-amine

cystamine CYS CA
Type Single Compound
Formula C4H12N2S2
Role graft
3

cis-aconityl

Type Single Compound
Formula -C6H6NO5
Role graft
4

adriblastin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material
5

cyanine 5.5

Cy5.5
Type Single Compound
Formula C40H46N2O5P
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on Cy5.5

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Applications

Area Application Nanomaterial Variant Source
diagnostics

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
3T3 (mouse fibroblast cell line)

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • HA
  1. 0shb58jRUVNFLwPRCwu4JXR8H
Product

Cy5.5/doxorubicin-loaded cis-aconityl-linked cystamine-grafted hyaluronic acid nanoparticles

Hydrodynamic diameter: 184.45 - 195.75 nm

Size: 100 - 150 nm

Medium/Support: none

References

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