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siRNA against luciferase-loaded zwitterionic amino lipid nanoparticles

Based on

21 Articles
2017 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

poly(ethylene imine)-graft-poly(ethylene glycol) copolymer

PEI25-PEG(2)10 PEI-PEG
Type Polymer
Formula
Role carriers
2

siEGFP

siRNA
Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
BALB/c mouse bearing MDA-MB-231 xenograft

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • [(2R)-2,3-di(octadecanoyloxy)propyl] 2-(trimethylazaniumyl)ethyl phosphate
  • cholesterol
  • C69H132N4O12S3
See all (4)
  1. b7F5VAqdVODjczLWaQ
Product

siRNA against luciferase-loaded zwitterionic amino lipid nanoparticles

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • [(2R)-2,3-di(octadecanoyloxy)propyl] 2-(trimethylazaniumyl)ethyl phosphate
  • cholesterol
  • C75H139N3O16S4
See all (4)
  1. 3eLfwXbHfoTEBzrTAX
Product

siRNA against luciferase-loaded zwitterionic amino lipid nanoparticles

Size: not specified

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • small interfering RNA targeting Plk1 mRNA
  • cross-linked polyethylenimine
  1. JJywRte8t
Product

siRNA against luciferase-loaded zwitterionic amino lipid nanoparticles

Diameter: ~ 66.9 - ~ 92.3 nm

Medium/Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • cholesterol
  • [(2R)-2,3-di(octadecanoyloxy)propyl] 2-(trimethylazaniumyl)ethyl phosphate
  • C77H147N3O12S3
See all (4)
  1. 7Ab1BxPoKrZjfuf3ax
Product

siRNA against luciferase-loaded zwitterionic amino lipid nanoparticles

Size: not specified

Medium/Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • small interfering RNA targeting Plk1 mRNA
  • cross-linked polyethylenimine
  1. wdHLZ0LkDcnRpG
Product

siRNA against luciferase-loaded zwitterionic amino lipid nanoparticles

Diameter: ~ 66.9 - ~ 92.3 nm

Medium/Support: none

References

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