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siRNA against luciferase-loaded zwitterionic amino lipid nanoparticles

Based on

21 Articles
2017 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

copolymer of poly(ethylene glycol) and poly-(L-lysine) grafting polyethylenimine

mPEG45-b-PLL42-g-(ss-lPEI15)10 mPEGn-b-PLLm-g-(ss-lPEIp)q mPEG-b-PLL-g-(ss-lPEI) PLI
Type Polymer
Formula
Role carriers
2

ribonucleic acid

XIAP siRNA siRNA
Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
BALB/c mouse bearing MDA-MB-231 xenograft

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • cholesterol
  • 3-({2-[3-({2-[bis(2-{[3-(octadecyloxy)-3-oxopropyl](propan-2-yl)amino}ethyl)amino]ethyl}(propan-2-yl)amino)propanamido]ethyl}dimethylazaniumyl)propane-1-sulfonate
  • lipid PEG2000
See all (4)
  1. eG8jDTJJT9s9e2CUJv3GFADqSLuyvl2QIJ02cJKT09zWzx5z2gVs
  2. 6uZz
  3. 65VeTboHSMw
Product

siRNA against luciferase-loaded zwitterionic amino lipid nanoparticles

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • 3-({2-[3-({2-[bis(2-{bis[3-(hexadecyloxy)-3-oxopropyl]amino}ethyl)amino]ethyl}[3-(decyloxy)-3-oxopropyl]amino)propanamido]ethyl}dimethylazaniumyl)propane-1-sulfonate
  • cholesterol
  • siRNA against luciferase
See all (4)
  1. dijJ4Ilo33BN3ZsjiUitYfRw51XKQLEGlCZ7gtNLt6QoNIg7mdha
  2. FExd
  3. Jxx9NqrtrGg
Product

siRNA against luciferase-loaded zwitterionic amino lipid nanoparticles

Size: not specified

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • cholesterol
  • 3-({2-[3-({3-[4-(3-{bis[3-(octadecyloxy)-3-oxopropyl]amino}propyl)piperazin-1-yl]propyl}[3-(decyloxy)-3-oxopropyl]amino)propanamido]ethyl}dimethylazaniumyl)propane-1-sulfonate
  • lipid PEG2000
See all (4)
  1. KuGRr5VeVJ8jd3FRYLukoLippYyfeynVYgEPss22WDyqz95NkmtP
  2. orOI
  3. k7ZmsLc6H8G
Product

siRNA against luciferase-loaded zwitterionic amino lipid nanoparticles

Size: not specified

Medium/Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • cholesterol
  • siRNA against luciferase
  • 3-{[2-(3-{[2-({3-[bis(2-hydroxydecyl)amino]propyl}(methyl)amino)ethyl](2-hydroxydecyl)amino}propanamido)ethyl]dimethylazaniumyl}propane-1-sulfonate
See all (4)
  1. JSZ12fxP5fXxkeDm49f71nzEzrm5Z81ZnLpyBjdUa1T394fwXnsi
  2. 2uVm
  3. bfuaZObBO8l
Product

siRNA against luciferase-loaded zwitterionic amino lipid nanoparticles

Size: not specified

Medium/Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • cholesterol
  • 3-({2-[3-({2-[bis({2-[(2-hydroxyhexadecyl)(methyl)amino]ethyl})amino]ethyl}(methyl)amino)propanamido]ethyl}dimethylazaniumyl)propane-1-sulfonate
  • siRNA against luciferase
See all (4)
  1. H9e9Vc2edpuqEuw2tXF7mzrb9c8tzPcQPamLpTqVrJOXfnNz7JEx
  2. RqEC
  3. K6UlisAuyxu
Product

siRNA against luciferase-loaded zwitterionic amino lipid nanoparticles

Size: not specified

Medium/Support: none

References

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