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folic acid-conjugated coumarin-545T-loaded poly(ethylene oxide)-based silica nanocapsules colloid

Based on

1 Articles
2016 Most recent source

Composition

1

water

Type Single Compound
Formula H2O
Role core
2

10-(benzothiazol-2-yl)-2,3,6,7-tetrahydro-1,1,7,7-tetramethyl-1H,5H,11H-benzopyropyrano(6,7,8-i,j)quinolizin-11-one

2,3,6,7-tetrahydro-1,1,7,7-tetramethyl-1H,5H,11H-10-(2-benzothiazolyl) quinolizino [9,9a,1gh]coumarin 2,3,6,7-tetrahydro-1,1,7,7-tetramethyl-1H,5H,11H-10-(2-benzothiazolyl)quinolizino-[9,9a,1gh]coumarin 2,3,6,7-tetrahydro-1,1,7,7-tetramethyl- 1H, 5H,11H-10-(2-benzothiazolyl) quinolizino coumarin coumarin-545T C545T
Type Single Compound
Formula C26H26N2O2S
Role loaded material
3

mixture of substance based on (PEO106PPO70PEO106-COOH/PEO106PPO70PEO106-COOH/PEO106PPO70PEO106/PEO106PPO70PEO106)

Type Complex Compound
Formula
Role layer
4

silicon dioxide

silicic oxide silica
Type Single Compound
Formula SiO2
Role layer
5

polyethylene glycol-folic acid

NH2-PEO-FA
Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Source
longitudinal magnetic resonance relaxivity

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Applications

Area Application Source
diagnostics

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Characterization

Method Source
dynamic light scattering

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Biological effects

Biological system Test details Source
human cervical cancer HeLa cells

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Preparation

Method 1

Type: Physical formation
Source:
Product

folic acid-conjugated coumarin-545T-loaded poly(ethylene oxide)-based silica nanocapsules colloid

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • PEO106PPO70PEO106
  • 10-(benzothiazol-2-yl)-2,3,6,7-tetrahydro-1,1,7,7-tetramethyl-1H,5H,11H-benzopyropyrano(6,7,8-i,j)quinolizin-11-one
  • PEO106PPO70PEO106-COOH
  1. mE5s9W1GhgYNaq7qdRNmkK91
Product

folic acid-conjugated coumarin-545T-loaded poly(ethylene oxide)-based silica nanocapsules colloid

References

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