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POSS-βCD/Ad-(Gd-DOTA)/Ad-PEG-cRGD/Ad-Cy5

Based on

1 Articles
2016 Most recent source

Composition

1

POSS-β-cyclodextrin

POSS-β-CD
Type Complex Compound
Formula
Role core
2

Ad-PEG-cRGD

Type Polymer
Formula
Role layer
3

2,2',2''-(10-(2-(1-adamantylamino)-2-oxoethyl)-1,4,7,10-tetraazacyclo-dodecane-1,4,7-triyl)triacetate gadolinium(III)

Ad-(Gd-DOTA)
Type Single Compound
Formula C26H40GdN5O7
Role layer
4

adamantyl sulfo-cyanine5

Ad-Cy5
Type Single Compound
Formula C42H52N3NaO8S2
Role layer

Properties

General physical and chemical properties

Property Value Source
longitudinal magnetic resonance relaxivity

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Applications

Area Application Source
diagnostics

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Characterization

Biological effects

Biological system Test details Source
BALB/c mice xenografted with breast cancer 4T1-GFP-Luc2 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • POSS-β-cyclodextrin
  • Ad-PEG-cRGD
  1. w3huiJ994rT3LBux
  2. Gvao4pNy
Product

POSS-βCD/Ad-(Gd-DOTA)/Ad-PEG-cRGD/Ad-Cy5

References

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