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spherical nucleic acid-nanoparticle conjugates with protein β-galactosidase core and dense shell of oligonucleotides

Based on

1 Articles
2015 Most recent source

Composition

1

β-galactosidase modified with AlexaFluor 647 C2 maleimide and NHS-PEG4-azide

β-gal functionalized with AlexaFluor 647 and NHS-PEG4-azide N3-functionalized β-gal
Type Nano Material
Formula
Role core
2

dibenzocyclooctyne-terminated oligonucleotide

DBCO-terminated oligonucleotide DBCO-DNA
Type Biomolecule
Formula
Role layer

Properties

Catalytic properties

Reaction Value Source
intracellular β-glycosidic linkage hydrolysis of 5-bromo-4-chloro-3-indolyl-β-D-galactopyranoside

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Applications

Area Application Source
catalysis

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Characterization

Method Source
circular dichroism

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Biological effects

Biological system Test details Source
C166 cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  1. 5TYHpPt
  2. HD7kf
  3. hU1nKZ
Product

spherical nucleic acid-nanoparticle conjugates with protein β-galactosidase core and dense shell of oligonucleotides

References

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