Fast insight into nanotechnology

Access easily searchable nanoscience data, synthesis methods and literature

mRNA-loaded lipid nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

1

phosphate buffer solution

PBS
Type Complex Compound
Formula
Role core
2

C12-200/DOPC

Type Complex Compound
Formula
Role layer
3

cholesterol

Type Single Compound
Formula C27H46O
Role loaded material
4

1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt)

C14-PEG 2000
Type Polymer
Formula
Role layer
5

human erythropoietin mRNA

EPO mRNA
Type Biomolecule
Formula
Role loaded material

Properties

Applications

Characterization

Biological effects

Biological system Test details Source
female C57BL/6 mice

More information available to subscribers only.

Or, view sample content

Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • cholesterol
  • 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
  • 1,1'-((2-(4-(2-((2-(bis(2-hydroxydodecyl)amino)ethyl)(2-hydroxydodecyl)amino)ethyl)piperazin-1-yl)ethyl)azanediyl)bis(dodecan-2-ol)
See all (4)
  1. 2Rj939WdFnnTeQl2XN
Product

mRNA-loaded lipid nanoparticles

Method 2

Type: Physical formation
Source:
Starting materials
  • cholesterol
  • 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
  • 1,1'-((2-(4-(2-((2-(bis(2-hydroxydodecyl)amino)ethyl)(2-hydroxydodecyl)amino)ethyl)piperazin-1-yl)ethyl)azanediyl)bis(dodecan-2-ol)
See all (4)
  1. 9gL12uo8CuVe5tdmnb
Product

mRNA-loaded lipid nanoparticles

Method 3

Type: Physical formation
Source:
Starting materials
  • cholesterol
  • 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
  • 1,1'-((2-(4-(2-((2-(bis(2-hydroxydodecyl)amino)ethyl)(2-hydroxydodecyl)amino)ethyl)piperazin-1-yl)ethyl)azanediyl)bis(dodecan-2-ol)
See all (4)
  1. jkeM7TZCjLAb6OfdIa
Product

mRNA-loaded lipid nanoparticles

References

Full content is available to subscribers only

To view content please choose from the following:

We use cookies to improve your experience with our site. More information

Sign up for a free trial