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DOX-loaded capsid-like nanocarriers

Based on

1 Articles
2016 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

glutamic acid-contained poly(L-leucine)

Type Polymer
Formula
Role core
2

octa(3-aminopropyl) silsesquioxane poly(L-lysine) dendrimer

Type Polymer
Formula
Role layer
3

adriblastin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
atomic force microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
4T1 multicellular tumor spheroids

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • doxorubicin hydrogen chloride
  1. qqYI7Sb9U7juy
  2. kVkL9SCLIOdVloh9
Product

DOX-loaded capsid-like nanocarriers

Diameter: ~ 150 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
Product

DOX-loaded capsid-like nanocarriers

Diameter: ~ 150 nm

Hydrodynamic diameter: 156.4 - 181.6 nm

Medium: phosphate buffer solution

Support: none

References

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