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doxorubicin-loaded PEG-PAC/PEG-PUC-based micelles

Based on

1 Articles
2014 Most recent source

Composition

1

poly(ethylene glycol)-b-poly(5-methyl-5-carboxyl-1,3-dioxan-2-one)

PEG-b-PAC PEG-PAC
Type Polymer
Formula
Role raw materials
2

poly(ethylene glycol)-b-poly(5-methyl-5-(phenylureaethyl)carboxyl-1,3-dioxan-2-one)

PEG-b-PUC PEG-PUC
Type Polymer
Formula
Role raw materials
3

doxorubicin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human breast cancer BT-474 cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • doxorubicin hydrogen chloride
  • poly(ethylene glycol)-b-poly(5-methyl-5-carboxyl-1,3-dioxan-2-one)
  • poly(ethylene glycol)-b-poly(5-methyl-5-(phenylureaethyl)carboxyl-1,3-dioxan-2-one)
  1. QHETwxaWG6fBp1fffCifFb4uxcitfXRk
  2. vb7wC63Raj1H8kfTJHHAu
Product

doxorubicin-loaded PEG-PAC/PEG-PUC-based micelles

Size: 87.8 - 91.4 nm

Medium: water

Support: none

References

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