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poly(lactic-co-glycolic acid)/siRNA nanoparticles colloid

Based on

1 Articles
2016 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

water

Type Single Compound
Formula H2O
Role core
2

small interfering RNA

small interfering RNA Cy5-siRNA siRNA
Type Biomolecule
Formula
Role loaded material
3

polyethylene glycol-b-poly(lactic-co-glycolic acid)

polyethylene glycol-b-polylactic acid PEG113-b-PLGA119/41 PEG5K-b-PLGA11K PEG113-b-PLA151 PEG5K-b-PLA11K
Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability

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Applications

Area Application Nanomaterial Variant Source
nanobiotechnology

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
female BALB/c nude mouse

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • polyethylene glycol-b-poly(lactic-co-glycolic acid)
  • water
  • small interfering RNA
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  2. L4o6WYxm1zJeWIPXKVfwNYjZ5dU69rJp8n1R4rbSRFyYHVerTp9OQifMBzBD1Gcg0GWbMdUdAVnQKY31li0fK43tD
  3. Desw0pmZQr
  4. cC2dAIIU
  5. 53frc
Product

poly(lactic-co-glycolic acid)/siRNA nanoparticles colloid

Hydrodynamic diameter: ~ 87 - ~ 500 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • polyethylene glycol-b-polylactic acid
  • water
  • small interfering RNA
  1. DVf7kuC2qz
  2. At28spqQpDwSurblW0568UGZqBXxNgyWbjmPMosdOKwPkQUrDH8B6Cmfe6nKg3dRpTLso5RtbMqKPxc3ZlJoaiJ5T
  3. yQTNRgUIjw
  4. kPnk2EqK
  5. T6mNQ
Product

poly(lactic-co-glycolic acid)/siRNA nanoparticles colloid

Hydrodynamic diameter: ~ 90 - ~ 500 nm

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
Product

poly(lactic-co-glycolic acid)/siRNA nanoparticles colloid

Size: not specified

Medium: phosphate buffer solution with fetal bovine serum

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
Product

poly(lactic-co-glycolic acid)/siRNA nanoparticles colloid

Size: not specified

Medium: phosphate buffer solution with fetal bovine serum

Support: none

References

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