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cisplatin-loaded nanoparticles composed of poly(γ,l-glutamic acid) and l-phenylalanine ethylester

Based on

1 Articles
2016 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

cis-diammineplatinum(II) dichloride

cis-platinum(ll)diamine dichloride cis-diamminedichloroplatinum(II) cis-dichlorodiammineplatinum(II) diammineplatinum(ll) dichloride cis-diamminedichloroplatinum cis-dichlorodiamminoplatinum cis-platinum (II) Pt(NH3)2Cl2 briplatin cisplatin platinol® CDDP CISP CPt
Type Single Compound
Formula PtCl2N2H6
Role core
2

l-phenylalanine ethylester modified poly(γ,l-glutamic acid)

L-PAE modified γ-PGA
Type Polymer
Formula
Role layer

Properties

Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
HeLa cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • cis-diammineplatinum(II) dichloride
  • l-phenylalanine ethylester modified poly(γ,l-glutamic acid)
Product

cisplatin-loaded nanoparticles composed of poly(γ,l-glutamic acid) and l-phenylalanine ethylester

Hydrodynamic diameter: 191.5 - 198.7 nm

Medium/Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • cis-diammineplatinum(II) dichloride
  • l-phenylalanine ethylester modified poly(γ,l-glutamic acid)
Product

cisplatin-loaded nanoparticles composed of poly(γ,l-glutamic acid) and l-phenylalanine ethylester

Hydrodynamic diameter: 95.1 - 104.9 nm

Medium/Support: none

References

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