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gadobutrol core/1,6-hexamethylenediamine shell nanocapsules

Based on

1 Articles
2016 Most recent source

Composition

1

1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid gadolinium complex

gadoteric acid gadobutrol Gadovist Gd-DOTA DOTA
Type Single Compound
Formula C16H24GdN4O8
Role core
2

hexamethylenediamine/toluene diisocyanate polymer

Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
gadobutrol release

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Applications

Area Application Nanomaterial Variant Source
diagnostics

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Characterization

Method Nanomaterial Variant Source
transmission electron microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
male Crl:NMRI mouse

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • hexamethylene-1,6-diamine
  • 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid gadolinium complex
  1. lx0aP
  2. Ez68
Product

gadobutrol core/1,6-hexamethylenediamine shell nanocapsules

Diameter: 55 - 630 nm

Medium/Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • 1,4-butylenediamine
  • 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid gadolinium complex
  1. UMhEb
  2. Q3Xo
Product

gadobutrol core/1,6-hexamethylenediamine shell nanocapsules

Diameter: 70 - 243 nm

Medium/Support: none

References

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