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pCMV-LUC-loaded lipo-nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

1

pCMV-LUC plasmid DNA

pCMV-LUC
Type Biomolecule
Formula
Role core
2

cholesterol

Type Single Compound
Formula C27H46O
Role layer
3

1,2-dioleoyl-3-dimethylammonium propane

1,2-dioleoyl-3-dimethylammonium propane 1,2-dioleoyl-3-dimethylammoniumpropane DODAP
Type Single Compound
Formula C41H77NO4
Role loaded material
4

1,2-di(9Z-octadecenoyloxy)-3-trimethylammonium-propane chloride

N-[1-(2,3-dioleoyloxy)propyl]-N,N,N-trimethylammonium chloride 1,2-di-(9Z-octadecenoyl)-3-trimethylammonium-propane chloride 1,2-dioleoyl-3-trimethyl-ammonium-propane (chloride salt) (1,2-dioleoyloxypropyl)-N,N,N-trimethylammonium chloride 1,2-dioleoyl-3-trimethylammonium-propane (chloride salt) 1,2-dioleoyl-3-trimethylammonium-propane chloride salt 1,2-dioleoyl-3-trimethylammoniumpropane chloride salt 1,2-dioleoyloxy-3-trimethylammonium-propane chloride 1,2-dioleoyl-3-trimethyl-ammonium-propane chloride (2,3-dioleoyloxypropyl)trimethylammonium chloride 1,2-dioleoyl-3-(trimethylammonio)propane chloride 1,2-dioleoyl-3-trimethylammonium-propane chloride 2,3-dioleoyloxy-propyl-trimethylammonium chloride 1,2-di-O-octadecenyl-3-trimethylammonium-propane 1,2-dioleoyl-3-trimethylammoniumpropane chloride dioleoyltrimethyl-ammoniumpropane chloride DOTAP (chloride salt) DOTAP chloride DOTAP DOTMA
Type Single Compound
Formula C42H80ClNO4
Role loaded material
5

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(lissamine rhodamine B sulfonyl) ammonium salt

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(lissamine rhodamine B sulfonyl) ammonium DOPE-Rhod DOPE-RhB
Type Single Compound
Formula C68H109N4O14PS2
Role loaded material
6

PEGylated cleavable lipo-peptide 1

PCL1
Type Complex Compound
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
stability dependent on heparin presence

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Biological effects

Biological system Test details Nanomaterial Variant Source
human embryonic kidney HEK293 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • cholesterol
  • 1,2-di(9Z-octadecenoyloxy)-3-trimethylammonium-propane chloride
  • 1,2-dioleoyl-3-dimethylammonium propane
See all (4)
  1. beMgoXRLjSGWdSwCjAszf5pTQ
Product

pCMV-LUC-loaded lipo-nanoparticles

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • cholesterol
  • 1,2-di(9Z-octadecenoyloxy)-3-trimethylammonium-propane chloride
  • 1,2-dioleoyl-3-dimethylammonium propane
See all (4)
  1. 2ZtO1GZ388Xu0t2YzdAh5XB8d
Product

pCMV-LUC-loaded lipo-nanoparticles

Size: not specified

Medium/Support: none

References

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