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anti-RRM2 siRNA-loaded adamantane/transferrin-conjugated polyethylene glycol-coated poly(cyclodextrin) nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

1

cyclodextrin

Type Biomolecule
Formula
Role core
2

adamantane-conjugated polyethylene glycol

AD-PEG
Type Polymer
Formula
Role partial layer
3

adamantane/transferrin-conjugated polyethylene glycol

AD-PEG-hTf
Type Polymer
Formula
Role partial layer
4

anti-RRM2 small-interfering RNA

anti-RRM2 siRNA
Type Biomolecule
Formula
Role loaded material

Properties

Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Biological effects

Biological system Test details Nanomaterial Variant Source
Hepa 1-6 murine hepatocellular carcinoma cell line-treated mouse

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • cyclodextrin
  • adamantane/transferrin-conjugated polyethylene glycol
  • adamantane-conjugated polyethylene glycol
Product

anti-RRM2 siRNA-loaded adamantane/transferrin-conjugated polyethylene glycol-coated poly(cyclodextrin) nanoparticles

Size: ~ 75 nm

Medium/Support: none

References

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