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plasmid DNA-loaded lipo-nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

1

plasmid DNA

Type Biomolecule
Formula
Role core
2

cholesterol

Type Single Compound
Formula C27H46O
Role layer
3

[(2R)-3-hexadecanoyloxy-2-[(Z)-octadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate

1-stearoyl-2- palmitoyl-sn-glycero-3-phosphocholine 1-palmitoyl-2-oleoyl-sn-glycero-3-phos-phocholine 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine 2-oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine palmitoyl-oleoyl-sn-glycero-phosphatidylcholine 1-palmitoyl-2-oleoylphosphatidylcholine palmitoyl oleoyl phosphatidylcholine palmitoyl-oleoyl-phosphatidylcholine palmitoyloleoyl-phosphatidylcholine palmitoyloleoylphosphatidyl choline Zwitterionic phosphatidylcholine soy phosphatidylcholine L-α-phosphatidylcholine phosphatidylcholine phospholipon 90 NG Phospholipon S100 PL S100 Egg-PC POPC POPS SPC PC EL
Type Single Compound
Formula C42H82NO8P
Role loaded material
4

1,2-di(9Z-octadecenoyloxy)-3-trimethylammonium-propane chloride

N-[1-(2,3-dioleoyloxy)propyl]-N,N,N-trimethylammonium chloride 1,2-di-(9Z-octadecenoyl)-3-trimethylammonium-propane chloride 1,2-dioleoyl-3-trimethyl-ammonium-propane (chloride salt) 1,2-dioleoyl-3-trimethylammonium-propane (chloride salt) (1,2-dioleoyloxypropyl)-N,N,N-trimethylammonium chloride 1,2-dioleoyl-3-trimethylammonium-propane chloride salt 1,2-dioleoyl-3-trimethylammoniumpropane chloride salt 1,2-dioleoyloxy-3-trimethylammonium-propane chloride 1,2-dioleoyl-3-trimethyl-ammonium-propane chloride (2,3-dioleoyloxypropyl)trimethylammonium chloride 1,2-dioleoyl-3-(trimethylammonio)propane chloride 1,2-dioleoyl-3-trimethylammonium-propane chloride 2,3-dioleoyloxy-propyl-trimethylammonium chloride 1,2-dioleoyl-3-trimethylammoniumpropane chloride 1,2-di-O-octadecenyl-3-trimethylammonium-propane dioleoyltrimethyl-ammoniumpropane chloride DOTAP (chloride salt) DOTAP chloride DOTAP DOTMA
Type Single Compound
Formula C42H80ClNO4
Role loaded material
5

1,2-dioleoyl-3-dimethylammonium propane

1,2-dioleoyl-3-dimethylammonium-propane 1,2-dioleoyl-3-dimethylammoniumpropane DODAP
Type Single Compound
Formula C41H77NO4
Role loaded material
6

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(lissamine rhodamine B sulfonyl) ammonium salt

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(lissamine rhodamine B sulfonyl) ammonium DOPE-Rhod DOPE-RhB
Type Single Compound
Formula C68H109N4O14PS2
Role loaded material
7

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]

DSPE-PEG2000 PE-PEG
Type Polymer
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Source
stability dependent on heparin presence

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Applications

Area Application Source
medicine/veterinary

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Characterization

Method Source
dynamic light scattering

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Biological effects

Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • [(2R)-3-hexadecanoyloxy-2-[(Z)-octadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate
  • cholesterol
  • 1,2-dioleoyl-3-dimethylammonium propane
See all (5)
  1. vyyHsiGASYkQ80gyefyh1EE9v
Product

plasmid DNA-loaded lipo-nanoparticles

References

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