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Cy5.5-grafted nebulized ultrasmall multimodal gadolinium-based contrast agents

Based on

1 Articles
2014 Most recent source

Composition

1

polysiloxane

Type Polymer
Formula
Role core
2

1,4,7,10-tetraazacyclododecane-N,-N',N'',N'''-tetraacetic acid

1,4,7,10- tetraazacyclododecane-1,4,7,10-tetraacetic acid 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid tetraazacyclododecane-1,4,7,10-tetraacetic acid cyclododecane DOTA CCD
Type Single Compound
Formula C16H28N4O8
Role layer
3

gadolinium(III) cation

gadolinium(III) ion gadolinium cation cationic Gd ion gadolinium(III) gadolinium ion gadolinium(3+) Gd(III) ion Gd(3+) ion Gd3+ ion Gd ion Gd(3+) Gd3+
Type Single Compound
Formula Gd3+
Role loaded material
4

cyanine 5.5

Cy5.5
Type Single Compound
Formula C40H46N2O5P
Role graft

Properties

Applications

Area Application Source
diagnostics

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Characterization

Biological effects

Biological system Test details Source
non-small-cell lung cancer tumor-bearing nude mouse

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Preparation

References

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