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DSF-loaded poly(ethylene glycol)-b-poly(lactide-co-glycolide)/poly(ε-caprolactone) nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

poly(ethylene glycol)-b-poly(lactide-co-glycolide)/poly(ε-caprolactone) mixture

mPEG-PLGA/PCL mixture
Type Complex Compound
Formula
Role carriers
2

disulfiram

DSF DS
Type Single Compound
Formula C10H20N2S4
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
critical micelle concentration

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
Balb/C mouse bearing 4T1 xenograft tumor

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • disulfiram
  • polycaprolactone
  • poly(ethylene glycol)-b-poly(lactide-co-glycolide)
  1. JXW
  2. CoJN3b8Q2d8a
Product

DSF-loaded poly(ethylene glycol)-b-poly(lactide-co-glycolide)/poly(ε-caprolactone) nanoparticles

Hydrodynamic radius: 80.7 - 101.7 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • disulfiram
  • polycaprolactone
  • poly(ethylene glycol)-b-poly(lactide-co-glycolide)
  1. xri
  2. lgDcZlpVaZRi
Product

DSF-loaded poly(ethylene glycol)-b-poly(lactide-co-glycolide)/poly(ε-caprolactone) nanoparticles

Hydrodynamic radius: 60.7 - 75.5 nm

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • disulfiram
  • polycaprolactone
  • poly(ethylene glycol)-b-poly(lactide-co-glycolide)
  1. qsK
  2. 0od4aMChOZ35
Product

DSF-loaded poly(ethylene glycol)-b-poly(lactide-co-glycolide)/poly(ε-caprolactone) nanoparticles

Hydrodynamic radius: 48.7 - 61.1 nm

Medium/Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • disulfiram
  • polycaprolactone
  • poly(ethylene glycol)-b-poly(lactide-co-glycolide)
  1. Bpd
  2. fyq0Rm9D1HjQ
Product

DSF-loaded poly(ethylene glycol)-b-poly(lactide-co-glycolide)/poly(ε-caprolactone) nanoparticles

Hydrodynamic radius: 73.0 - 91.6 nm

Medium/Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • disulfiram
  • polycaprolactone
  • poly(ethylene glycol)-b-poly(lactide-co-glycolide)
  1. 8kj
  2. yooXIersr4YV
Product

DSF-loaded poly(ethylene glycol)-b-poly(lactide-co-glycolide)/poly(ε-caprolactone) nanoparticles

Hydrodynamic radius: 65.8 - 76.6 nm

Medium/Support: none

References

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