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TRAIL-decorated platelet membrane-coated DOX-loaded acrylamide nanovehicles

Based on

1 Articles
2015 Most recent source

Composition

1

DOX-loaded acrylamide nanovehicles

NV
Type Nano Material
Formula
Role core
2

platelet membrane

Type Bioobject
Formula
Role layer
3

mercapto moiety

thiol terminus thiol moiety thiol group
Type Single Compound
Formula HS-
Role layer
4

-C12H15N2O4

Type Single Compound
Formula -C12H15N2O4
Role layer
5

tumor necrosis factor-related apoptosis-inducing ligand

TRAIL
Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on pH

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
female nude mouse bearing circulating human breast adenocarcinoma MDA-MB-231 cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  1. 9ufc6xAb8l
Product

TRAIL-decorated platelet membrane-coated DOX-loaded acrylamide nanovehicles

Hydrodynamic size: ~ 20 - ~ 150 nm

Medium/Support: none

References

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