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lapatinib-loaded PCS100/Chol/DSPE-MPEG2000 liposomes colloid

Based on

1 Articles
2014 Most recent source

Composition

1

phosphate buffer solution

PBS
Type Complex Compound
Formula
Role core
2

mixture of substance based on (N-(carbonyl-methoxy polyethylene glycol-2000)-1,2-distearoyl-sn-glycero-3-phosphoethanolamine/N-(carbonyl-methoxy polyethylene glycol-2000)-1,2-distearoyl-sn-glycero-3-phosphoethanolamine/egg L-α-phosphatidylcholine/egg L-α-phosphatidylcholine)

Type Complex Compound
Formula
Role layer
3

cholesterol

Type Single Compound
Formula C27H46O
Role loaded material
4

lapatinib

Type Single Compound
Formula C29H26ClFN4O4S
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on fetal bovine serum

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
atomic force microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
breast cancer BT474 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • N-(carbonyl-methoxy polyethylene glycol-2000)-1,2-distearoyl-sn-glycero-3-phosphoethanolamine
  • cholesterol
  • lapatinib
See all (4)
  1. ggOcTutXTcJAg5uESWn17tykcfMViA
Product

lapatinib-loaded PCS100/Chol/DSPE-MPEG2000 liposomes colloid

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Product

lapatinib-loaded PCS100/Chol/DSPE-MPEG2000 liposomes colloid

Hydrodynamic diameter: 104.0 - 108.4 nm

Medium: PB buffer

Support: none

References

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