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folate acid-modified pyropheophorbide-lipid/cholesterol/PEG-DSPE porphysomes

Based on

1 Articles
2014 Most recent source

Composition

1

phosphate buffer solution

PBS
Type Complex Compound
Formula
Role core
2

mixture of substance based on (1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-folate(polyethylene glycol)/1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-folate(polyethylene glycol)/C57H82N5O9P/C57H82N5O9P)

Type Complex Compound
Formula
Role layer
3

cholesterol

Type Single Compound
Formula C27H46O
Role loaded material

Properties

General physical and chemical properties

Property Value Source
singlet oxygen generation dependent on laser beam irradiation

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Applications

Area Application Source
medicine/veterinary

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Characterization

Method Source
fluorescence spectroscopy

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Biological effects

Biological system Test details Source
female nu/nu nude mouse bearing KB cells xenograft

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • cholesterol
  • 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-folate(polyethylene glycol)
  • C57H82N5O9P
  1. Cr16LfRFHOpy
Product

folate acid-modified pyropheophorbide-lipid/cholesterol/PEG-DSPE porphysomes

References

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