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GW3965-loaded poly(D,L-lactide)-b-poly(ethylene glycol)/poly(D,L-lactide-co-glycolide)-GW3965 nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

1

3-[3-[N-(2-chloro-3-trifluoromethylbenzyl)-(2,2-diphenylethyl)amino]propyloxy]phenylacetic acid hydrochloride

GW3965
Type Single Compound
Formula C33H32Cl2F3NO3
Role core
2

poly(D,L-lactide-co-glycolide)-GW3965

PLGA-GW3965
Type Polymer
Formula
Role layer
3

poly(D,L-lactide)-b-poly(ethylene glycol)

PLA9K-PEG2K PLA-PEG
Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Source
drug release

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Applications

Characterization

Method Source
dynamic light scattering

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Biological effects

Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • poly(D,L-lactide)-b-poly(ethylene glycol)
  • poly(D,L-lactide-co-glycolide)-GW3965
  • 3-[3-[N-(2-chloro-3-trifluoromethylbenzyl)-(2,2-diphenylethyl)amino]propyloxy]phenylacetic acid hydrochloride
  1. wQb4Vs69wZfXI8cwWXh0ARH
Product

GW3965-loaded poly(D,L-lactide)-b-poly(ethylene glycol)/poly(D,L-lactide-co-glycolide)-GW3965 nanoparticles

Method 2

Type: Physical formation
Source:
Starting materials
  • poly(D,L-lactide)-b-poly(ethylene glycol)
  • poly(D,L-lactide-co-glycolide)-GW3965
  • 3-[3-[N-(2-chloro-3-trifluoromethylbenzyl)-(2,2-diphenylethyl)amino]propyloxy]phenylacetic acid hydrochloride
  1. lInzuiRFl3TKvj4s7V34aol
Product

GW3965-loaded poly(D,L-lactide)-b-poly(ethylene glycol)/poly(D,L-lactide-co-glycolide)-GW3965 nanoparticles

Method 3

Type: Physical formation
Source:
Starting materials
  • poly(D,L-lactide)-b-poly(ethylene glycol)
  • poly(D,L-lactide-co-glycolide)-GW3965
  • 3-[3-[N-(2-chloro-3-trifluoromethylbenzyl)-(2,2-diphenylethyl)amino]propyloxy]phenylacetic acid hydrochloride
  1. vEYKQr6JuV5HEBEOznbknXC
Product

GW3965-loaded poly(D,L-lactide)-b-poly(ethylene glycol)/poly(D,L-lactide-co-glycolide)-GW3965 nanoparticles

Method 4

Type: Physical formation
Source:
Starting materials
  • poly(D,L-lactide)-b-poly(ethylene glycol)
  • poly(D,L-lactide-co-glycolide)-GW3965
  • 3-[3-[N-(2-chloro-3-trifluoromethylbenzyl)-(2,2-diphenylethyl)amino]propyloxy]phenylacetic acid hydrochloride
  1. uCKXyfsdGdrSUNFUFZyufj8
Product

GW3965-loaded poly(D,L-lactide)-b-poly(ethylene glycol)/poly(D,L-lactide-co-glycolide)-GW3965 nanoparticles

Method 5

Type: Physical formation
Source:
Starting materials
  • poly(D,L-lactide)-b-poly(ethylene glycol)
  • poly(D,L-lactide-co-glycolide)-GW3965
  • 3-[3-[N-(2-chloro-3-trifluoromethylbenzyl)-(2,2-diphenylethyl)amino]propyloxy]phenylacetic acid hydrochloride
  1. DdWMu3n5H51rYLlJpz4xjoQ
Product

GW3965-loaded poly(D,L-lactide)-b-poly(ethylene glycol)/poly(D,L-lactide-co-glycolide)-GW3965 nanoparticles

References

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