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GW3965-encapsulating phosphatidylserine/poly(lactic-co-glycolic acid)-b-polyethylene glycol nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

1

poly(lactic-co-glycolic acid)-b-polyethylene glycol

poly(DL-lactic-co-glycolic acid) PLGA-b-PEG
Type Polymer
Formula
Role carriers
2

3-[3-[N-(2-chloro-3-trifluoromethylbenzyl)-(2,2-diphenylethyl)amino]propyloxy]phenylacetic acid hydrochloride

GW3965
Type Single Compound
Formula C33H32Cl2F3NO3
Role loaded material
3

phosphatidylserine

Type Complex Compound
Formula
Role layer

Properties

General physical and chemical properties

Property Value Source
drug release

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Applications

Area Application Source
medicine/veterinary

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Characterization

Method Source
dynamic light scattering

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Biological effects

Biological system Test details Source
C57Bl/6J Ldlr<sup>-/-</sup> mouse

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 3-[3-[N-(2-chloro-3-trifluoromethylbenzyl)-(2,2-diphenylethyl)amino]propyloxy]phenylacetic acid hydrochloride
  • poly(lactic-co-glycolic acid)-b-polyethylene glycol
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Product

GW3965-encapsulating phosphatidylserine/poly(lactic-co-glycolic acid)-b-polyethylene glycol nanoparticles

References

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