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SN-38-loaded micelles

Based on

1 Articles
2016 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

polycaprolactone

PCL
Type Polymer
Formula
Role core
2

poly(2-(dimethylamino)ethyl methacrylate)

PDMA
Type Polymer
Formula
Role layer
3

(7-ethyl-10-hydroxycamptothecin)

7-ethyl-10-hydroxy camptothecin 7-ethyl-10-hydroxy-camptothecin 7-ethyl-10-hydroxycamptothecin SN-38 SN38
Type Single Compound
Formula C22H20N2O5
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human colon adenocarcinoma LS174T cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
Product

SN-38-loaded micelles

Diameter: 151.0 - 173.3 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • (7-ethyl-10-hydroxycamptothecin)
  • PDMA-block-poly(ε-caprolactone)
  1. y78ss70CKbr19NUUg
  2. CVOIhEoMJ
Product

SN-38-loaded micelles

Size: not specified

Medium/Support: none

References

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