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SN-38/USPIO-loaded siRNA micelleplexes

Based on

1 Articles
2016 Most recent source

Composition

1

polycaprolactone

PCL
Type Polymer
Formula
Role core
2

poly(2-(dimethylamino)ethyl methacrylate)

PDMA
Type Polymer
Formula
Role layer
3

(7-ethyl-10-hydroxycamptothecin)

7-ethyl-10-hydroxy camptothecin 7-ethyl-10-hydroxy-camptothecin 7-ethyl-10-hydroxycamptothecin SN-38 SN38
Type Single Compound
Formula C22H20N2O5
Role loaded material
4

ultra-small superparamagnetic iron oxide nano- particles

ultra-small superparamagnetic iron oxide nanoparticles superparamagnetic iron oxide magnetic tracer superparamagnetic iron oxide nanoparticles magnetic iron oxide nanoparticles iron oxide magnetic nanoparticles ferumoxytol nanoparticles iron oxide nanoparticles magnetic nanoparticles FeOx nano-dot centers SPIO magnetic tracer FexOy nanoparticles USPIO nanoparticles SPIO nanoparticles FeOx nanoparticles iron oxide NPs iron oxide NP Feraheme® FexOy NP FeOx NP Sienna+ IO NP SPION USPIO IONP MNP
Type Nano Material
Formula
Role loaded material
5

VEGF siRNA

Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human colon adenocarcinoma LS174T cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
Product

SN-38/USPIO-loaded siRNA micelleplexes

Diameter: 237.6 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  1. IW5bbaqxUmI2Capx
  2. t73kPo87
Product

SN-38/USPIO-loaded siRNA micelleplexes

Size: not specified

Medium/Support: none

References

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