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pEGFP-loaded reversible-PEGylated histidylated polyplex nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

reversible-PEGylated polylysine

mPEG-SS-PLL
Type Polymer
Formula
Role binder
2

pEGFP plasmid DNA

Type Biomolecule
Formula
Role fillers

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
stability

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Applications

Area Application Nanomaterial Variant Source
nanobiotechnology

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
female BALB/c nude mouse with human cervical cancer HeLa cells xenograft

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • pEGFP plasmid DNA
  • NaCl aqueous solution
  • reversible-PEGylated polylysine
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  2. ibo1ar
  3. V0C
Product

pEGFP-loaded reversible-PEGylated histidylated polyplex nanoparticles

Hydrodynamic diameter: ~ 250 - ~ 300 nm

Medium: NaCl aqueous solution

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • pEGFP plasmid DNA
  • histidylated reversible-PEGylated polylysine
  • NaCl aqueous solution
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  2. J1PysU
  3. W9O
Product

pEGFP-loaded reversible-PEGylated histidylated polyplex nanoparticles

Hydrodynamic diameter: ~ 250 - ~ 375 nm

Medium: NaCl aqueous solution

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • histidylated reversible-PEGylated polylysine
  • pEGFP plasmid DNA
  • NaCl aqueous solution
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  2. uX28Ev
  3. pbD
Product

pEGFP-loaded reversible-PEGylated histidylated polyplex nanoparticles

Diameter: 50 - 70 nm

Hydrodynamic diameter: ~ 160 - ~ 325 nm

Medium: NaCl aqueous solution

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • pEGFP plasmid DNA
  • histidylated reversible-PEGylated polylysine
  • NaCl aqueous solution
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  2. OpyJGZ
  3. BtN
Product

pEGFP-loaded reversible-PEGylated histidylated polyplex nanoparticles

Hydrodynamic diameter: ~ 200 - ~ 350 nm

Medium: NaCl aqueous solution

Support: none

References

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