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PLGA-b-HA nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

poly(lactic-co-glycolic acid)

PLGA
Type Polymer
Formula
Role core
2

1,4-butylenediamine

butane-1,4-diamine 1,4-butanediamine 1,4-diaminobutane diaminobutane putrescine BDA D88 BD
Type Single Compound
Formula C4H12N2
Role layer
3

hyaluronic acid

HA
Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability dependent on pH

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
atomic force microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
human breast adenocarcinoma MCF-7 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • poly(lactic-co-glycolic acid)-block-hyaluronic acid
  1. iqVfIXUGqFrHJ1lOtim7CvGnstUcq2hhzT
  2. qPKMPFsO
Product

PLGA-b-HA nanoparticles

Size: 128.0 - 157.6 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • poly(lactic-co-glycolic acid)-block-hyaluronic acid
  1. qtaePhrA8pWbNsu5lI5JpgeJaC1sodzqTa
  2. Kyc1n9qq
Product

PLGA-b-HA nanoparticles

Size: 188.0 - 197.2 nm

Medium: water

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • poly(lactic-co-glycolic acid)-block-hyaluronic acid
  1. NWvpv6ngMAn6KZ0cDVmcStQLjRvKpvaanh
  2. QYzI3N54
Product

PLGA-b-HA nanoparticles

Size: ~ 80 nm

Medium/Support: none

Method 4

Type: Physical formation
Source:
Starting materials
Product

PLGA-b-HA nanoparticles

Size: 108.2 - 115.0 nm

Medium: water

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • poly(lactic-co-glycolic acid)-block-hyaluronic acid
  1. q52WTTY7wNQoUR1twKcHzeQ84Dy8u3RUvf
  2. 2M3KLBYV
Product

PLGA-b-HA nanoparticles

Size: 153.5 - 165.5 nm

Medium: water

Support: none

References

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