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coumarin 6-loaded PGA-based nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

1

phosphate buffer solution

PBS
Type Complex Compound
Formula
Role core
2

3-(1,3-benzothiazol-2-yl)-7-(diethylamino)-2H-chromen-2-one

3-(2-benzothiazolyl)-N,N-diethylumbelliferylamine 3-(2-benzothiazolyl)-7-(diethylamino)coumarin 6-coumarin coumarin 6 coumarin-6 C6 dye Cou6 C-6
Type Single Compound
Formula C20H18N2O2S
Role loaded material
3

des-octanoyl ghrelin-poly(ethylene glycol-g-glutamate)-co-poly(distearin-g-glutamate)

des-octanoyl ghrelin-PEGGM-PDSGM
Type Polymer
Formula
Role layer

Properties

Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
mouse brain microvascular endothelial (bEnd3) cell and rat astrocytes (CTX TNA2) cell co-culture (BBB model)

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 3-(1,3-benzothiazol-2-yl)-7-(diethylamino)-2H-chromen-2-one
  • des-octanoyl ghrelin-poly(ethylene glycol-g-glutamate)-co-poly(distearin-g-glutamate)
  • phosphate buffer solution
  1. o0SQIE9VboYLMhJryQxLFu3p73
Product

coumarin 6-loaded PGA-based nanoparticles

Diameter: ~ 150 nm

Geometric radius: 92.9 - 93.7 nm

Gyration radius: 90.6 - 91.2 nm

Hydrodynamic diameter: 146.2 - 147.0 nm

Medium/Support: none

References

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