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doxorubicin-loaded cationic polymeric liposomes

Based on

1 Articles
2016 Most recent source

Composition

1

water

Type Single Compound
Formula H2O
Role core
2

mixture of substance based on ((2-aminoethoxy)({2,3-bis[(9Z)-octadec-9-enoyloxy]propoxy})phosphinic acid/tetradecyl-quaternized carboxymethyl chitosan)

Type Complex Compound
Formula
Role layer
3

cholesterol

Type Single Compound
Formula C27H46O
Role loaded material
4

doxorubicin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on pH

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
female BALB/c nude mouse bearing SMMC-7721 tumor

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • tetradecyl-quaternized carboxymethyl chitosan
  • (2-aminoethoxy)({2,3-bis[(9Z)-octadec-9-enoyloxy]propoxy})phosphinic acid
  • doxorubicin
See all (5)
  1. Ow4fyI4MMtOYBaBy9elekxcaRN
Product

doxorubicin-loaded cationic polymeric liposomes

Hydrodynamic diameter: 132.8 - 139.6 nm

Medium: water

Support: none

References

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