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Ps-siRNA polyplexes

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

pullulan/spermine

Ps
Type Biomolecule
Formula
Role carriers
2

EGFP siRNA

Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability dependent on nitrogen-phosphorus ratio

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Applications

Area Application Nanomaterial Variant Source
genetic engineering

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Characterization

Method Nanomaterial Variant Source
atomic force microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
human human breast adenocarcinoma MDA-MB-231-GFP cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
Product

Ps-siRNA polyplexes

Hydrodynamic diameter: ~ 200 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
Product

Ps-siRNA polyplexes

Hydrodynamic diameter: ~ 300 nm

Medium: serum solution

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
Product

Ps-siRNA polyplexes

Hydrodynamic diameter: ~ 400 nm

Medium: serum solution

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
Product

Ps-siRNA polyplexes

Hydrodynamic diameter: ~ 600 nm

Medium: serum solution

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • EGFP siRNA
  • pullulan/spermine
  1. oiLwnl4usCGT5nkA
Product

Ps-siRNA polyplexes

Diameter: ~ 120 nm

Medium/Support: none

References

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