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sorafenib-loaded iRGD-functionalized carbonized porous silicon nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

1

p-type silicon

p-Si
Type Complex Compound
Formula
Role core
2

(3-aminopropyl)-triethoxysilane moiety

(3-aminopropyl)trimethoxysilane moiety (3-aminopropyl)triethoxysilane moiety γ-aminopropyltriethoxy silane moiety 3-aminopropyltrimethoxysilane moiety 3-aminopropyltriethoxysilane moiety γ-aminopropyltriethoxysilane moiety (3-aminopropyl)trioxysilane moiety (3-aminopropyl)silanetrioxy group 3-aminopropylsilanetrioxy group 3-aminopropylsiloxy fragment 3-aminopropyl silane moiety 3-aminopropylsilane moiety γ-APTES moiety 3-APTS moiety APTES moiety APTMS moiety AMPS moiety APTS moiety APS moiety
Type Single Compound
Formula -C3H8NO3Si-
Role layer
3

[(1R,8S,9S)-bicyclo[6.1.0]non-4-yn-9-yl]methyl hydrogen carbonate

Type Single Compound
Formula C11H14O3
Role layer
4

iRGD

Type Biomolecule
Formula
Role loaded material
5

glass-like carbon

vitreous carbon glassy carbon carbon GC
Type Single Compound
Formula C
Role loaded material
6

4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide

sorafenib SFN SOR SF
Type Single Compound
Formula C21H16ClF3N4O3
Role loaded material

Properties

General physical and chemical properties

Property Value Source
drug release dependent on fetal bovine serum

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Applications

Area Application Source
medicine/veterinary

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Characterization

Biological effects

Biological system Test details Source
EA.hy926 endothelial cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  1. v6Tq27I
Product

sorafenib-loaded iRGD-functionalized carbonized porous silicon nanoparticles

References

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