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plasmid DNA-loaded DPc/poly(ethylene glycol)-poly{N-[N-(2-aminoethyl)-2-aminoethyl]aspartamide}-poly(L-lysine) nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

1

poly(ethylene glycol)-poly{N-[N-(2-aminoethyl)-2-aminoethyl]aspartamide}-poly(L-lysine)

PEG-PAsp(DET)-PLys
Type Polymer
Formula
Role carriers
2

deoxyribonucleic acid

DNA
Type Biomolecule
Formula
Role loaded material
3

mixture of substance based on (-C56H41O23/-C56H41O23/porphyrin/porphyrin)

Type Complex Compound
Formula
Role layer

Properties

Applications

Area Application Nanomaterial Variant Source
genetic engineering

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human cervical cancer cells (HeLa)

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • poly(ethylene glycol)-poly{N-[N-(2-aminoethyl)-2-aminoethyl]aspartamide}-poly(L-lysine)
  1. MsSDvKXNzOAwHp2sqbLL7
Product

plasmid DNA-loaded DPc/poly(ethylene glycol)-poly{N-[N-(2-aminoethyl)-2-aminoethyl]aspartamide}-poly(L-lysine) nanoparticles

Hydrodynamic diameter: ~ 87 nm

Medium/Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • poly(ethylene glycol)-poly{N-[N-(2-aminoethyl)-2-aminoethyl]aspartamide}-poly(L-lysine)
  1. hai6fMwjBZTd5PI9d9RF6
Product

plasmid DNA-loaded DPc/poly(ethylene glycol)-poly{N-[N-(2-aminoethyl)-2-aminoethyl]aspartamide}-poly(L-lysine) nanoparticles

Hydrodynamic diameter: ~ 91 nm

Medium/Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • poly(ethylene glycol)-poly{N-[N-(2-aminoethyl)-2-aminoethyl]aspartamide}-poly(L-lysine)
  1. dbrcnU0KqKpdKWzxaZkp0
Product

plasmid DNA-loaded DPc/poly(ethylene glycol)-poly{N-[N-(2-aminoethyl)-2-aminoethyl]aspartamide}-poly(L-lysine) nanoparticles

Hydrodynamic diameter: ~ 89 nm

Medium/Support: none

Method 4

Type: Chemical synthesis
Source:
Starting materials
  • poly(ethylene glycol)-poly{N-[N-(2-aminoethyl)-2-aminoethyl]aspartamide}-poly(L-lysine)
  1. yE2JUSvDEkhfWAcI2xqyR
Product

plasmid DNA-loaded DPc/poly(ethylene glycol)-poly{N-[N-(2-aminoethyl)-2-aminoethyl]aspartamide}-poly(L-lysine) nanoparticles

Hydrodynamic diameter: ~ 88 nm

Medium/Support: none

References

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