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PEG-p(L-LA)-DTPA-Gd:PEG-p(L-His) mixed micelles

Based on

1 Articles
2014 Most recent source

Composition

1

methoxy poly(ethylene glycol)-b-poly(L-histidine)

PEG-p(L-His)
Type Polymer
Formula
Role raw materials
2

methoxy poly(ethylene glycol)-b-poly(L-lactic acid)-diethylenetriaminopentaacetic acid dianhydride-gadolinium chelate

PEG-p(L-LA)-DTPA-Gd
Type Polymer
Formula
Role raw materials

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
longitudinal magnetic resonance relaxivity

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
BALB/c nude mouse with murine tumor CT26 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
Product

PEG-p(L-LA)-DTPA-Gd:PEG-p(L-His) mixed micelles

Hydrodynamic diameter: ~ 40 nm

Medium: aqueous solution

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • methoxy poly(ethylene glycol)-b-poly(L-histidine)
  • methoxy poly(ethylene glycol)-b-poly(L-lactic acid)-diethylenetriaminopentaacetic acid dianhydride-gadolinium chelate
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Product

PEG-p(L-LA)-DTPA-Gd:PEG-p(L-His) mixed micelles

Diameter: ~ 15 nm

Medium/Support: none

References

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