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doxorubicin-loaded HPPH-lipid/1,2-distearoyl-sn-glycero-3-phosphocholine/1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-poly(ethylene glycol)/cholesterol/HEPES buffer liposomes

Based on

1 Articles
2014 Most recent source

Composition

1

HEPES buffer

Type Complex Compound
Formula
Role core
2

adriblastin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material
3

[(2R)-2,3-di(octadecanoyloxy)propyl] 2-(trimethylazaniumyl)ethyl phosphate

non-deuterated 1,2-distearoyl-sn-glycero-3-phosphocholine 1,2-distearoyl-sn-glycerol-3-phosphatidylcholine 1,2-distearoyl-sn-glycero-3-phosphatidylcholine 1,2-dioctadecanoyl-sn-glycero-3-phosphocholine L-α 1,2-distearoyl-sn-glycero-3-phosphocholine 1,2-distearoyl-sn-glycero-3-phosphorylcholine hydrogenated soy sn-glycero-3-phosphocholine 1,2-dipalmitoyl-sn-glycero-3-phosphocholine 1,2-Distearoyl-sn-glycero-3-phosphocholine 1,2-distearoyl-sn-glycero-3-phosphocholine hydrogenated soy L-α-phosphatidylcholine hydrogenated soybean phosphatidylcholine distearoyl-sn-glycero-3-phosphocholine hydrogenated soya phosphatidylcholine hydrogenated soy phosphatidylcholine Hydrogenated soy phosphatidylcholine hydrogenated L-α-phosphatidylcholine distearyl-L-α-phosphatidylcholine distearoyl phosphatidylcholine distearyl phosphatidyl choline distearoylphosphatidylcholine L-α-phosphatidylcholine egg PC hDSPC DSPC HSPC DSCP
Type Single Compound
Formula C44H88NO8P
Role layer
4

C63H96N5O10P

Type Single Compound
Formula C63H96N5O10P
Role loaded material
5

1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-poly(ethylene glycol) 2000

1,2-distearoyl-sn-glycero-3- phosphoethanolamine-N-(methoxy(PEG)-2000) DSPE-PEG
Type Polymer
Formula
Role loaded material
6

cholesterol

Type Single Compound
Formula C27H46O
Role loaded material

Properties

General physical and chemical properties

Property Value Source
drug release dependent on time

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Applications

Area Application Source
medicine/veterinary

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Characterization

Method Source
cryo-electron microscopy

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Biological effects

Biological system Test details Source
female mouse bearing Human carcinoma (KB) cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • cholesterol
  • [(2R)-2,3-di(octadecanoyloxy)propyl] 2-(trimethylazaniumyl)ethyl phosphate
  • 1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-poly(ethylene glycol) 2000
See all (4)
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  2. cWN4Vri
Product

doxorubicin-loaded HPPH-lipid/1,2-distearoyl-sn-glycero-3-phosphocholine/1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-poly(ethylene glycol)/cholesterol/HEPES buffer liposomes

References

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