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Cy5-loaded irinotecan/riboflavin-containing PEG-based polymer nanoparticles

Based on

2 Articles
2016 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

irinotecan/riboflavin-containing PEG-based polymer nanoparticles

NP(AZO-S-Ir/R)
Type Nano Material
Formula
Role carriers
2

cyanine 5 dye

cyanine 5 Cy 5 Cy5
Type Single Compound
Formula C33H40N2O8S2
Role loaded material

Properties

Applications

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
CD1 mouse after injection with pro-inflammatory cytokine tumor necrosis factor α

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • cyanine 5 dye
  • irinotecan-modified polyethyleneglycol-based 4-phenylazobenzoic acid derivative
  1. eHeEIgpA5YTmIYmsO6yqfhwYw9vGRSU4DifOTCGbhjGqtLw8aURwIRmFcSwV5XI4ZmV
Product

Cy5-loaded irinotecan/riboflavin-containing PEG-based polymer nanoparticles

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • cyanine 5 dye
  • riboflavin-modified polyethyleneglycol-based 4-phenylazobenzoic acid derivative
  • irinotecan-modified polyethyleneglycol-based 4-phenylazobenzoic acid derivative
  1. mbQIWLiscBiEnYDc3pKADaRgDxNvuTlvrfFfReyxnH5mVpeAAlNGmK1mGhaLoSid4jX
Product

Cy5-loaded irinotecan/riboflavin-containing PEG-based polymer nanoparticles

Size: not specified

Medium/Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • bovine serum albumin
  1. mZlqo4V5i3Fu2FtN
  2. 7pHyiUT
  3. Sal8g2
Product

Cy5-loaded irinotecan/riboflavin-containing PEG-based polymer nanoparticles

Hydrodynamic diameter: 80 - 120 nm

Medium/Support: none

References

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