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Pc4-loaded σ-2 receptor targeting-ligand functionalized triple-responsive expansile nanogel particles

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

MBA-PDA-PEG-PNiPMA

Type Polymer
Formula
Role carriers
2

silicon phthalocyanine photosensitizer Pc 4

Pc 4 Pc4
Type Single Compound
Formula C40H37N9OSi2
Role loaded material

Properties

General physical and chemical properties

Property Value Source
transition temperature

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Applications

Area Application Source
medicine/veterinary

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Characterization

Biological effects

Biological system Test details Source
head and neck squamous cell carcinoma UMSCC22A cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • poly[(2-(pyridin-2-yldisulfanyl))-co-[poly(ethylene glycol)]]-poly(N-isopropyl methacrylamide)
  • silicon phthalocyanine photosensitizer Pc 4
  • 4-methoxybenzoic acid-poly[(2-(pyridin-2-yldisulfanyl))-co-[poly(ethylene glycol)]]-poly(N-Isopropyl methacrylamide)
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Product

Pc4-loaded σ-2 receptor targeting-ligand functionalized triple-responsive expansile nanogel particles

Method 2

Type: Physical formation
Source:
Starting materials
  • poly[(2-(pyridin-2-yldisulfanyl))-co-[poly(ethylene glycol)]]-poly(N-isopropyl methacrylamide)
  • silicon phthalocyanine photosensitizer Pc 4
  • 4-methoxybenzoic acid-poly[(2-(pyridin-2-yldisulfanyl))-co-[poly(ethylene glycol)]]-poly(N-Isopropyl methacrylamide)
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  3. eBfvMq
Product

Pc4-loaded σ-2 receptor targeting-ligand functionalized triple-responsive expansile nanogel particles

Method 3

Type: Physical formation
Source:
Starting materials
  • poly[(2-(pyridin-2-yldisulfanyl))-co-[poly(ethylene glycol)]]-poly(N-isopropyl methacrylamide)
  • silicon phthalocyanine photosensitizer Pc 4
  • 4-methoxybenzoic acid-poly[(2-(pyridin-2-yldisulfanyl))-co-[poly(ethylene glycol)]]-poly(N-Isopropyl methacrylamide)
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Product

Pc4-loaded σ-2 receptor targeting-ligand functionalized triple-responsive expansile nanogel particles

References

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