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doxorubicin-loaded SPION-embedded reducible polyamidoamine-graft-poly(ethylene glycol)/dodecylamine nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

1

reducible polyamidoamine-graft-poly(ethylene glycol)/dodecylamine

rPAA-DD-PEG
Type Polymer
Formula
Role binder
2

oleic acid-coated iron oxide nanoparticles

superparamagnetic iron oxide nanoparticles oleic acid-coated magnetic nanoparticles oleic acid capped Fe3O4 nanoparticles modified iron oxide nanoparticles modified magnetite nanoparticles modified Fe3O4 nanoparticles oleic acid-capped Fe3O4 NP Fe3O4 nanoparticles Fe3O4@OA OA@SPION SPION
Type Nano Material
Formula
Role fillers
3

adriblastin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material

Properties

General physical and chemical properties

Property Value Source
drug release dependent on dithiothreitol concentration

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Applications

Area Application Source
medicine/veterinary

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Characterization

Method Source
transmission electron microscopy

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Biological effects

Biological system Test details Source
female BALB/c nude mouse bearing MDA-MB-231 human breast cancer tumor xenograft

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Preparation

Method 1

Type: Physical formation
Source:
  1. ORt
  2. eQSNhS3ndpCNX7YP
Product

doxorubicin-loaded SPION-embedded reducible polyamidoamine-graft-poly(ethylene glycol)/dodecylamine nanoparticles

References

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