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DNA-loaded lipid nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

HEPES buffer

Type Complex Compound
Formula
Role core
2

lipid mixture

Type Complex Compound
Formula
Role layer
3

protamine

Type Biomolecule
Formula
Role loaded material
4

plasmid DNA

pDNA
Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Source
Zeta potential

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Applications

Area Application Source
genetic engineering

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Characterization

Method Source
dynamic light scattering

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Biological effects

Biological system Test details Source
human fibrosarcoma cells (HT1080)

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • cholesterol
  • 1-stearoyl-2-oleoyl sn-glycero-3-phosphatidylethanolamine
  • 1-(monomethoxy-polyethyleneglycol2000)-2,3-dimyristoylglycerol
See all (4)
  1. 00ixBGM
Product

DNA-loaded lipid nanoparticles

References

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