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3-(glycidoxypropyl) triethoxysilane/cystamine/adamantanecarboxylic acid/β-cyclodextrin/ethanolamine-functionalized poly(glycidyl methacrylate) gene vector functionalized hollow silica nanoparticles with 10-hydroxycamptothecin

Based on

1 Articles
2015 Most recent source

Composition

1

hollow silica nanoparticles

Type Nano Material
Formula
Role core
2

3-(glycidoxypropyl) triethoxysilane

glycidyloxypropyl triethoxysilane 3-glycidoxypropyltriethoxysilane Dynasylan® GLYEO GLYEO GPTS
Type Single Compound
Formula C12H26O5Si
Role layer
3

cystamine

CYS CA
Type Single Compound
Formula C4H12N2S2
Role layer
4

adamantanecarboxylic acid

Ad-COOH
Type Single Compound
Formula C11H16O2
Role layer
5

10-hydroxycamptothecin

hydroxycamptothecin 10-HCPT HCPT CPT
Type Single Compound
Formula C20H16N2O5
Role loaded material
6

β-cyclodextrin/ethanolamine-functionalized poly(glycidyl methacrylate) gene vector

CD-PGEA gene vector
Type Complex Compound
Formula
Role layer

Properties

General physical and chemical properties

Property Value Source
drug release dependent on glutathione

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Applications

Area Application Source
drug delivery

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Characterization

Method Source
atomic force microscopy

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Biological effects

Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  1. Qve9CT1jNHt0QfyXY67d
  2. W4wzhbqP
  3. fLlB
Product

3-(glycidoxypropyl) triethoxysilane/cystamine/adamantanecarboxylic acid/β-cyclodextrin/ethanolamine-functionalized poly(glycidyl methacrylate) gene vector functionalized hollow silica nanoparticles with 10-hydroxycamptothecin

Method 2

Type: Physical formation
Source:
Starting materials
  1. YBPmFI7JJryIbcURbOvw
  2. r4xqqCqE
  3. SVbQ
Product

3-(glycidoxypropyl) triethoxysilane/cystamine/adamantanecarboxylic acid/β-cyclodextrin/ethanolamine-functionalized poly(glycidyl methacrylate) gene vector functionalized hollow silica nanoparticles with 10-hydroxycamptothecin

Method 3

Type: Physical formation
Source:
Starting materials
  1. MBbawWdELB5Kbd7K8wZt
  2. UNndcEtn
  3. 63BO
Product

3-(glycidoxypropyl) triethoxysilane/cystamine/adamantanecarboxylic acid/β-cyclodextrin/ethanolamine-functionalized poly(glycidyl methacrylate) gene vector functionalized hollow silica nanoparticles with 10-hydroxycamptothecin

Method 4

Type: Physical formation
Source:
Starting materials
  1. AmnNGxXlgtiYv6bJTKic
  2. tkaC2glC
  3. y7ZA
Product

3-(glycidoxypropyl) triethoxysilane/cystamine/adamantanecarboxylic acid/β-cyclodextrin/ethanolamine-functionalized poly(glycidyl methacrylate) gene vector functionalized hollow silica nanoparticles with 10-hydroxycamptothecin

Method 5

Type: Physical formation
Source:
Starting materials
  1. G8EBNlOq1qsYJY2hL0eJ
  2. 63mIh909
  3. z4fV
Product

3-(glycidoxypropyl) triethoxysilane/cystamine/adamantanecarboxylic acid/β-cyclodextrin/ethanolamine-functionalized poly(glycidyl methacrylate) gene vector functionalized hollow silica nanoparticles with 10-hydroxycamptothecin

References

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