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siRNA nanoplexes armed with glutamyl-methotrexate ligands

Based on

1 Articles
2016 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

Inf7 peptide-modified siRNA

siEG5-Inf7
Type Biomolecule
Formula
Role core
2

K(dPEG24-E62-MTX)-K(Stp4-C)2

Type Complex Compound
Formula
Role layer

Properties

Applications

Area Application Source
medicine/veterinary

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Characterization

Biological effects

Biological system Test details Source
human cervix carcinoma KB cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • Inf7 peptide-modified siRNA
  • K(dPEG24-E4-MTX)-K(Stp4-C)2
  1. dngoc6T3JdkY2siS87nhkzJqftslh4FgNFMoRJWZz3SYlDAZM0
  2. TBc
Product

siRNA nanoplexes armed with glutamyl-methotrexate ligands

Method 2

Type: Physical formation
Source:
Starting materials
  • Inf7 peptide-modified siRNA
  • K(dPEG24-E62-MTX)-K(Stp4-C)2
  1. 7c7e5DP4VhQU7412YocQ6EtPhRa5UaNpUEZVL6QUyYABnAQKJh
  2. 23R
Product

siRNA nanoplexes armed with glutamyl-methotrexate ligands

Method 3

Type: Physical formation
Source:
Starting materials
  • Inf7 peptide-modified siRNA
  • K(dPEG24-E4-MTX)-K(Stp4-C)2
  1. J168r0HLbqp5M9hnzth9zSA1vqCtKwgoNL39hM0Tolv7T5ZUOf
  2. qFE
Product

siRNA nanoplexes armed with glutamyl-methotrexate ligands

Method 4

Type: Physical formation
Source:
Starting materials
  • Inf7 peptide-modified siRNA
  • K(dPEG24-E2-MTX)-K(Stp4-C)2
  1. gEAow0R5CTxrc3D45wVpLWROROlUiCgDmkalwBx981g0nqvdbl
  2. DkV
Product

siRNA nanoplexes armed with glutamyl-methotrexate ligands

Method 5

Type: Physical formation
Source:
Starting materials
  • K(dPEG24-E62-MTX)-K(Stp4-C)2
  • Inf7 peptide-modified siRNA
  1. Ro74IlF5k0jXLvstum9jPpet170bJWR4jUcTwYk3vBBt6IoKnU
  2. yDX
Product

siRNA nanoplexes armed with glutamyl-methotrexate ligands

References

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