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DOPE/CHEMS-coated EGFR siRNA-loaded peptidomimetic nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

C51H85N9O5

Type Single Compound
Formula C51H85N9O5
Role core
2

DOPE/CHEMS lipid layer

Type Complex Compound
Formula
Role layer
3

enhanced green fluorescent protein small interfering RNA

EGFR siRNA
Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Characterization

Biological effects

Biological system Test details Nanomaterial Variant Source
human non-small cell lung carcinoma H1299 cell line expressing EGFP

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • cholesteryl hemisuccinate
  • (2-aminoethoxy)({2,3-bis[(9Z)-octadec-9-enoyloxy]propoxy})phosphinic acid
  1. LFcnAHaUc2
Product

DOPE/CHEMS-coated EGFR siRNA-loaded peptidomimetic nanoparticles

Size: ~ 400 nm

Medium: HEPES buffer

Support: none

References

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