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back-filled orthopyridyldisulfide polyethyleneglycol N-hydroxysuccinimide ester-modified fluorescent labeled herceptin-conjugated gold nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

1

gold nanoparticles

Au nanoparticles gold nanospheres Au nanospheres gold NP gold NS Au NP Au NS AuNP AuNS GNP GNS
Type Nano Material
Formula
Role core
2

thiol-terminated polyethyleneglycol N-hydroxysuccinimide ester moiety

HS-PEG-NHS ester moiety
Type Polymer
Formula
Role layer
3

fluorescent labeled herceptin

Type Biomolecule
Formula
Role layer
4

methoxy-terminated PEG

mPEG-SH
Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability in presence of serum

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Applications

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
ErbB2-negative MCF7 cells

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Preparation

Method 1

Type: Physical formation
Source:
Product

back-filled orthopyridyldisulfide polyethyleneglycol N-hydroxysuccinimide ester-modified fluorescent labeled herceptin-conjugated gold nanoparticles

Size: not specified

Medium: HEPES buffer

Support: none

Method 2

Type: Chemical synthesis
Source:
  1. CuoyaYRqTZB5pbCm
Product

back-filled orthopyridyldisulfide polyethyleneglycol N-hydroxysuccinimide ester-modified fluorescent labeled herceptin-conjugated gold nanoparticles

Size: not specified

Medium/Support: none

Method 3

Type: Physical formation
Source:
Product

back-filled orthopyridyldisulfide polyethyleneglycol N-hydroxysuccinimide ester-modified fluorescent labeled herceptin-conjugated gold nanoparticles

Hydrodynamic diameter: 96.8 - 98.0 nm

Medium: phosphate buffer solution

Support: none

References

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