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ctEGF targeted Au NP/RNase A/anti-MDR1 DNA nanocomplex

Based on

1 Articles
2014 Most recent source

Composition

1

gold

Type Single Compound
Formula Au
Role core
2

single-stranded deoxyribonucleic acid

ssDNA
Type Biomolecule
Formula
Role layer
3

amino-modified single-stranded deoxyribonucleic acid

amino-modified ssDNA
Type Biomolecule
Formula
Role layer
4

NHS-PEG-maleimide crosslinker

Type Polymer
Formula
Role layer
5

[C4]-monothiol Cys-tagged EGF

epidermal growth factor ctEGF
Type Biomolecule
Formula
Role layer
6

ribonuclease A

RNase A
Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Source
stability under proteinase K activity

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Applications

Area Application Source
medicine/veterinary

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Characterization

Method Source
dynamic light scattering

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Biological effects

Biological system Test details Source
firefly luciferase (Fluc) mRNA

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  1. WYTw47cnh3Y9GjXkGHON25D8i0wrBrq0vzhXeIQAnADKyZ
  2. XzYS3dc
Product

ctEGF targeted Au NP/RNase A/anti-MDR1 DNA nanocomplex

Method 2

Type: Physical formation
Source:
Product

ctEGF targeted Au NP/RNase A/anti-MDR1 DNA nanocomplex

Method 3

Type: Chemical synthesis
Source:
Starting materials
  1. myoa1c8BX0qQ58kgzE1fTWLEt6l9Tpn8XzjtCDiyIxtwdI
  2. ou75htr
Product

ctEGF targeted Au NP/RNase A/anti-MDR1 DNA nanocomplex

Method 4

Type: Chemical synthesis
Source:
Starting materials
  1. pY2qs3zHktbF8HGzV36q1vs9D7k0twQMUkby5LNXA3dKRS
  2. EQFKDHq
Product

ctEGF targeted Au NP/RNase A/anti-MDR1 DNA nanocomplex

References

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