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prostate-specific membrane antigen-targeted nanoplexes

Based on

1 Articles
2016 Most recent source

Composition

1

poly(iminoethylene)

polyethyleneimine polyaziridine PEI
Type Polymer
Formula
Role carriers
2

pEGFP-TRAIL

Type Biomolecule
Formula
Role loaded material
3

PI-PEG-Maleimide-SATP

Type Polymer
Formula
Role graft
4

succinimidyl 4-formylbenzoate

SFB
Type Single Compound
Formula C8H5O3
Role graft
5

SATP-PLL-SANH

SATP-PLL-SANH
Type Polymer
Formula
Role raw materials
6

cytosine deaminase

bCD
Type Biomolecule
Formula
Role raw materials

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Catalytic properties

Reaction Value Nanomaterial Variant Source
5-fluorocytosine deamination

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human prostate cancer PC3 cells transfected to PSMA (PC3-PIP) overexpression

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Preparation

Method 1

Type: Physical formation
Source:
Product

prostate-specific membrane antigen-targeted nanoplexes

Size: ~ 230 nm

Medium: water

Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • N-succinimidyl-S-acetylthiopropionate
  • poly(iminoethylene)
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Product

prostate-specific membrane antigen-targeted nanoplexes

Size: not specified

Medium/Support: none

References

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