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mPEG-PLGAeporphyrin micelles encapsulating doxorubicin and docetaxel

Based on

1 Articles
2016 Most recent source

Composition

1

water

Type Single Compound
Formula H2O
Role core
2

mPEG-PLGA-porphyrin

Type Polymer
Formula
Role layer
3

adriblastin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material
4

1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}

docetaxel Taxotere Dtxl Doc Dtx
Type Single Compound
Formula C43H53NO14
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
BALB/c mouse xenografted with human breast adenocarcinoma mda-mb-231 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
Product

mPEG-PLGAeporphyrin micelles encapsulating doxorubicin and docetaxel

Size: ~ 120 nm

Medium: phosphate buffer solution

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • adriblastin
  • water
Product

mPEG-PLGAeporphyrin micelles encapsulating doxorubicin and docetaxel

Size: not specified

Medium/Support: none

References

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