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poly(tetraguanidinium-derived disulfide)-coated Alexa Fluor 647-labeled siRNA nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

1

Alexa Fluor 647-labeled siRNA nanoparticles

Type Nano Material
Formula
Role raw materials
2

poly(tetraguanidinium-derived disulfide)

PTEGGu4
Type Polymer
Formula
Role layer

Properties

Applications

Area Application Nanomaterial Variant Source
diagnostics

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Characterization

Method Nanomaterial Variant Source
fluorescence correlation spectroscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
Hep3B cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
Product

poly(tetraguanidinium-derived disulfide)-coated Alexa Fluor 647-labeled siRNA nanoparticles

Hydrodynamic diameter: 7.3 - 7.9 nm

Medium: none

Support: HEPES buffer

Method 2

Type: Chemical synthesis
Source:
Starting materials
Product

poly(tetraguanidinium-derived disulfide)-coated Alexa Fluor 647-labeled siRNA nanoparticles

Hydrodynamic diameter: 8.4 - 9.2 nm

Medium: none

Support: HEPES buffer

Method 3

Type: Chemical synthesis
Source:
Starting materials
Product

poly(tetraguanidinium-derived disulfide)-coated Alexa Fluor 647-labeled siRNA nanoparticles

Hydrodynamic diameter: 6.6 nm

Medium: none

Support: HEPES buffer

Method 4

Type: Chemical synthesis
Source:
Starting materials
Product

poly(tetraguanidinium-derived disulfide)-coated Alexa Fluor 647-labeled siRNA nanoparticles

Hydrodynamic diameter: 4.8 - 5.6 nm

Medium: none

Support: phosphate buffer solution

References

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