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siRNA nanoplexes armed with glutamyl-methotrexate ligands

Based on

1 Articles
2016 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

Cy5-labeled siAHA1

Cy5-labeled siRNA
Type Biomolecule
Formula
Role core
2

K(dPEG24-αMTX)-K(Stp4-C)2

Type Complex Compound
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
fluorescence correlation spectroscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
human alveolar adenocarcinoma A549 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • Cy5-labeled siAHA1
  • K(dPEG24-αMTX)-K(Stp4-C)2
  1. hTjkBlWFF8jlR1XHSS3kmdZTEDDUWFbFK71u4BTQZq13FE9L8n
  2. pvE
Product

siRNA nanoplexes armed with glutamyl-methotrexate ligands

Hydrodynamic diameter: 5.3 - 5.9 nm

Medium: HEPES buffer

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • Cy5-labeled siAHA1
  • K(dPEG24-MTX)-K(Stp4-C)2
  1. IZdwTrCSRddIdybO5B1DtgI9JZKRrW7RwmhQzQYS00Gnb87Gjs
  2. KwA
Product

siRNA nanoplexes armed with glutamyl-methotrexate ligands

Hydrodynamic diameter: 5.3 - 5.9 nm

Medium: HEPES buffer

Support: none

References

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